By G. F. Rossi (auth.), Professor Jan Gybels, Professor Edward R. Hitchcock, Priv.-Doz. Christoph Ostertag, Professor Gian Franco Rossi, Professor Jean Siegfried, Professor Gabor Szikla (eds.)
Local interstitial radiation treatment of intrinsic and inaccessible mind tumors is faced with significant difficulties: 1. The tolerance of standard mind tissue, that's often keen on neighborhood tumor irradiation, i.e. perifocal white subject edema and demyelinating results, is essential. 2. facts on radiation results of implanted radioactive assets on neoplastic tissue, i.e. facts at the radiosensitivity and at the biology of tumors, are nonetheless greatly unavailable. In medical perform the dose with which to accomplish a given quantity of tumor necrosis is approximately predicted. This record bargains with the experimental findings of Iodine-125 and Iridium-I92 everlasting implants in fit and neoplastic mind tissue. Our personal experimental findings are correlated with experimental information on Yttnul11-l)O irradiation from the literature. The research is directed to gather information at the tolerance non-tumoral mind tissue and to aim to set up a dose-response dating. Morphologic adjustments within the puppy mind Following Interstitial Iodine-125 Irradiation Iodine-I25 seeds (manufactured by way of three M corporation, St. Paul, M. N.) with an job of 3.55 mCi have been completely implanted below stereotactic stipulations into the subcortical white subject of the gyrus coronalis of the left hemisphere in 6 beagle canine. One animal with a non-radioactive seed implanted lower than comparable operative stipulations served as a keep an eye on. The animals have been allowed to outlive 25, forty six, seventy one, ninety four, 248, 368 days, respectively, after the implantation. The keep watch over animal survived forty six days. an in depth description of the experimental approach is given in other places sixteen. 17.
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Additional resources for Advances in Stereotactic and Functional Neurosurgery 6: Proceedings of the 6th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Rome 1983
Epilepsy and the functional anatomy of the human brain, 896p. London: J. A. Churchill ed. 1954. 11. , A propos des deviations oculaires dans les crises epileptiques debut occipital, 84 p. Paris: These. 1978. 12. , Stereotaxic exploration and therapy in epilepsy. In: Handbook of Neurology, vol. XV (1974), 758-782. 13. , Investigations fonctionnelles dans l'epilepsie. Rev. Neurol. 105 (1961), 119130. 14. , Approche nouvelle de la neurochirurgie de l'epilepsie. Rev. Neurochir. 20 (1974), Supp!. 20, 240 p.
LO. Jackson, J. , On the anatomical, physiological and pathological investigation of epilepsies. West Riding Lunatic Asylum Medical Reports 3 (1873), 315. Reprinted in: Selected Writings of John Hughlings Jackson, edited by J. Taylor, 1 (1931), 90-111. London: Hoddler and Stoughton. II. Kuhl, D. , Phelps, M. , Epileptic patterns of local cerebral metabolism and perfusion in humans determined by emission computed tomography of 18FDG and 13NH3. Ann. Neurol. 8 (1980),348360. 12. McNaughton, F. , Criteria for selection of patients for neurosurgical treatment.
1964 20-10' 80 , - Mil L3 JIJI'lIl. ,,~ "J "Ii ! ,.. l 11 Ie' , O l . ill 1' ~LA L3 • , !... INQew 0. " i " " " -'>c "I -"1 Fig. 6. Power spectra of the 32 channels shown in Fig. 5. Interval numbers (window) 5, 7 and 9. Very clearly the channel number 5, which represents the activity of the left hippocampus, dominates this early seizure stage . " " (MAKNEU - l .. J /llYGIIIlA L[IT rwu w 4S 5J ..... 075 ",.. os Fig. 7. Compressed spectral array plot (left) of the seizure activity ofleft amygdala shown in Fig.
Advances in Stereotactic and Functional Neurosurgery 6: Proceedings of the 6th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Rome 1983 by G. F. Rossi (auth.), Professor Jan Gybels, Professor Edward R. Hitchcock, Priv.-Doz. Christoph Ostertag, Professor Gian Franco Rossi, Professor Jean Siegfried, Professor Gabor Szikla (eds.)