By Hiroshi Mitsumoto MD
Amyotrophic Lateral Sclerosis provides the main entire, clinically-focused details on ALS (Lou Gehrig's illness) in print. the 3 authors, well known for his or her paintings during this sector, offer cohesive and balanced assurance of this syndrome, together with the background, scientific positive factors, pathology and pathogenesis, remedy and administration of ALS. To facilitate knowing, each one bankruptcy is superior by means of finished tables and figures, in addition to specified bankruptcy summaries.
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Additional resources for Amyotrophic Lateral Sclerosis
Goldblatt, D: Motor neuron disease: Historical introduction. In Norris, FH and Kurland, LT (eds): Motor Neuron Diseases. Grune & Stratton, New York, 1969, pp 3-11. 16 Introduction to ALS 28. Gowers, WR: A Manual of Diseases of the Nervous System, vol 1, ed 3. Plakiston, Philadelphia, 1899, pp 531-558. 29. Greenfield, JG: Amyotrophic lateral sclerosis. In Greenfield, JG, Blackwood, W, McMenemey, WH, et al (eds): Neuropathology. Arnold, London, 1958, pp 545-548. 30. Haymaker, W and Schiller, F: The Founders of Neurology, ed 2.
They thought that "classic" motor neuron disease was not well defined but rather was a prominent band within a wide spectrum of subacute or chronic multiple system degenerations that show a predilection to certain parts of the motor system. In 1971, Metcalf and Hirano46 reported on two members of a family with PMA and a third member with classic ALS, suggesting that PMA is only a clinical manifestation of ALS. New Forms of ALS Guamanian ALS-Parkinsonism-Dementia Complex. Although a nosographic description of ALS and motor neuron disease was in progress in the early part of this century, an ALS-like disease on the Mariana Islands, particularly Guam, was newly recognized.
Again, if LMN signs develop subsequently, the designation of ALS is indicated. In a small number of patients in whom the disease has an LMN History, Terminology, and Classification of ALS onset, UMN signs never develop; then the condition is referred to as PMA. Similarly, in a small percentage of patients with UMN-onset disease, LMN signs do not develop, and the disease is termed PLS. Although PMA and PLS may be the opposite ends of the spectrum of ALS (the subsets of ALS), we believe they should be viewed as independent conditions.
Amyotrophic Lateral Sclerosis by Hiroshi Mitsumoto MD