By Professor Klaus Kayser M.D., Ph.D. (auth.)
All illnesses regarding the lung are provided in alphabetical order. each one is mentioned within the related method lower than the subheadings of definition, epidemiology, pathophysio- logy, medical diagnosis, radiology, gross and micro patho- logy, histomorphological descriptors, precise stains, corridor- mark of prognosis and differential diagnosis.
"An encyclopedic choice of phrases facing illnesses and/or pathological stipulations of the respiration organs with the purpose to offer the reader fast information regarding the basic features. This encyclopedic resource could be suggested not just to pathologists but in addition to clinicians and practitioners confronted with pulmonary diseases." (Experimental and Toxicologic Pathology)
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Additional resources for Analytical Lung Pathology
An extracellular mucus production is infrequent, in contrast to PAS-positive granules within the cytoplasm of tumor cells. Bronchioloalveolar carcinoma shows two different growth beha30 viors: The majority of patients suffer from solid, central scarred tumors with "lined up" tumor cells along the interalveolar septula at the tumor boundary. Additional acinar appearance of tumor textures is frequent. The tumor cells are small, and the tumor cell nuclei show mainly a coarse chromatin distribution.
Peripheral tumors are often ball-like or ellipsoidally shaped. Histology: According to the WHO classification (1982) the following four categories of adenocarcinoma should be distinguished: 1. acinar adenocarcinoma 2. papillary adenocarcinoma 3. bronchioloalveolar adenocarcinoma 4. solid adenocarcinoma The subclassification is, however, obscured by the fact that the majority of adenocarcinomas show mixtures of the different categories depending upon their differentiation. The grading of adenocarcinoma is divided as usual into three categories: well differentiated, moderately differentiated, and poorly differentiated adenocarcinoma.
Pathology: Gross: Firm tumour masses of white, pink, or light tan color with spreading growth along the bronchus or trachea. At a later stage invasion into adjacent structures and polypoid intraluminal growth can occur. The overlying mucosa is usually unsuspicious, but at a later stage ulceration may occur. The boundaries of the tumors in the submucosa are difficult to detect. Histology: The characteristic texture of the tumor results from the formation of cystic glands built up of monolayers of epithelial tumor cells mixed with "filled-up" glandular structures, both being embedded in broad bundles ofhyalinized stroma.
Analytical Lung Pathology by Professor Klaus Kayser M.D., Ph.D. (auth.)