Download e-book for kindle: Atlas of Medical Renal Pathology by Stephen M. Bonsib (auth.)

By Stephen M. Bonsib (auth.)

ISBN-10: 1461471494

ISBN-13: 9781461471493

ISBN-10: 1461471508

ISBN-13: 9781461471509

The kidney is an organ with advanced organogenesis prone to a variety of misadventures in improvement and is uncovered to a various array of insults of hematogenous and decrease urinary tract foundation. This Atlas of scientific Renal Pathology presents an outline of the improvement, macroscopic and microscopic beneficial properties of the traditional kidney. this is often via a complete survey of developmental and cystic kidney ailments, vascular illnesses and tubulointerstitial illnesses. An emphasis is put on gross diagnostic findings with special histological correlates. moreover, the histological, immunofluorescent, immunohistochemical and ultrastructural good points of the key glomerular ailments and renal transplantation pathology are offered. This compendium of non-neoplastic kidney ailments illustrates the overwhelming majority ailments you will definitely come upon in surgical and post-mortem pathology.

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Over-rotation results in a posterior or a lateral pelvis and ureter. This is very uncommon. 2 2 Renal Ectopia Renal ectopia indicates an abnormal location of one or more kidneys. Their location may be pelvic, abdominal, above the normal renal fossa and subdiaphragmatic, thoracic, or in the opposite renal fossa. Fig. 2 Renal ectopia. This is pelvic renal ectopia. The kidney did not “ascend” from the pelvis as would be normal. Notice that its ureter is anterior, thus the kidney is also nonrotated.

The capillary loops are lined by fenestrated endothelium whose nucleus is characteristically located near the mesangial interface. The capillary loops are covered on their external surface by podocytes (visceral epithelial cells). Situated between the podocytes and endothelial cells is the glomerular basement membrane (GBM). The GBM is composed of three layers: the lamina rara externa, lamina densa, and lamina rara interna. Podocytes consist of a cell body with cell processes that terminate in slender foot processes oriented perpendicular to the GBM.

The renal abnormalities will not always be identical, even in the face of a common distal obstruction. This case of urethral obstruction is secondary to posterior urethral valve. It shows a large multicystic left kidney and a much smaller, albeit still dysplastic, right kidney Fig. 85 Urethral atresia without renal dysplasia. In most cases with in utero complete urinary tract obstruction, bilateral renal dysplasia is an expected finding. However, there are exceptions. This fetus shows massive abdominal distension due to urethral atresia.

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Atlas of Medical Renal Pathology by Stephen M. Bonsib (auth.)

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