By T. Wiegel, INTERNATIONAL SYMPOSIUM ON SPECIAL ASPEC
This quantity discusses diagnostic and healing options together with present arguable matters within the administration of gastrointestinal tumors. detailed emphasis is given to rectal and pancreatic melanoma. the 1st half provides the most recent diagnostic advancements for rectal melanoma with a spotlight at the position of preoperative radiotherapy and radio-chemotherapy. additionally thought of is the surgical means of overall mesorectal excision. Recurrent rectal melanoma is one other very important factor lower than dialogue. a wide component to the ebook is dedicated to the prognosis and interdisciplinary remedy of pancreatic melanoma. Controversies in regards to the function of adjuvant radiochemotherapy are provided intimately. the ultimate half is devoted to the remedy of liver metastases and describes the result of surgical resection and new healing techniques reminiscent of in situ ablation and radiosurgery. This publication deals an interdisciplinary standpoint on gastrointestinal tumor remedy.
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Extra resources for Controversies in Gastrointestinal Tumor Therapy: 6th International Symposium on Special Aspects of Radiotherapy, Berlin, September 5-7, 2002 (Frontiers of Radiation Therapy and Oncology)
The shortcomings of our study are that computed tomograms were mainly used to evaluate disease extension in the pelvis (CT in 94% and MRI in 32%) and tumor spread may therefore be underestimated. Only a minority of patients (12%) had laparotomy or laparoscopy for restaging and disease evaluation. Only 17% of the patients evaluated had previously been treated with radiotherapy and, of those, recurrences were within the treated volume in 81%. It is therefore unlikely that our results are influenced by the inclusion of these patients as our results fit the previously reported results of other studies quite well.
Höcht/Hammad/Thiel/Wiegel/Siegmann/Willner/Wust/ Herrmann/Eble/Carstens/Flentje/Neumann/Hinkelbein 46 Fig. 5. Sites of recurrence after abdominoperineal resection: areas involved in less than 10% excluded. Fig. 6. Differences in extension of tumor recurrences after LAR vs. APR. , and have dramatic impacts on the quality of life of the afflicted patients. Once the tumor has recurred, chances of cure are small even when extensive resections and multimodality treatment strategies are applied, and only patients with small recurrent tumors at the site of the anastomosis seem to fare better [14–17].
Recommendations for radiation ports in adjuvant therapy should hence be based on the recurrence patterns of patients treated recently, but many of the studies reporting on pelvic recurrence patterns have some limitations; they are either outdated or do not give exact anatomic information on the location of recurrent tumors within the pelvis, or they just simply cover a very large time span within which changes in therapy will very likely have happened, thus compromising the ability to make their results a basis for recommendations in planning target volumes in adjuvant radiotherapy [12, 13, 15, 27–32].
Controversies in Gastrointestinal Tumor Therapy: 6th International Symposium on Special Aspects of Radiotherapy, Berlin, September 5-7, 2002 (Frontiers of Radiation Therapy and Oncology) by T. Wiegel, INTERNATIONAL SYMPOSIUM ON SPECIAL ASPEC